Extravasation Risk Factors - Concurrent Medication

The following medications prescribed concurrently with an intravenous solution may increase the risk of extravasation.

Medication	Risk
Anticoagulants Antifibrinolytics Antiplatelets	May exacerbate extravasation or cause a compartmental injury by increasing local bleeding
Vasodilators	May increase local blood flow and enlarge the area of injury
Hormone Therapy	Vasodilating properties
Steroids	Vasodilating properties
Diuretics	May increase local blood flow
Antihistamines	May constrict capillaries and arterioles, resulting in ischaemic injury
Analgesics	Reduced pain sensation may cause less reporting of extravasations
IV antibiotics	Repeated venous insult may thrombose vessels

This page last updated 06/01/2004